Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985797 | 0.88 | ACKR3 (0.51) | ACKR3TP53LMNATHRBSTAT3 | |
| SCHEMBL7989896 | 0.85 | ACKR3 (0.49) | ACKR3TP53LMNATHRBSTAT3 | |
| SCHEMBL7989610 | 0.85 | ACKR3 (0.50) | ACKR3TP53LMNATHRBMAPT | |
| SCHEMBL7981945 | 0.83 | KDM4E (0.44) | TP53LMNANAMPT | |
| SCHEMBL7987167 | 0.81 | KDM4E (0.45) | TP53LMNANAMPTL3MBTL1MAPT | |
| SCHEMBL7983600 | 0.80 | MCHR1 (0.40) | NAMPTALDH1A1TSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL7972387 | 0.79 | SLC6A2 (0.41) | NAMPTALDH1A1L3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7986019 | 0.79 | SLC6A2 (0.41) | NAMPTALDH1A1L3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7972006 | 0.79 | SLC6A2 (0.41) | NAMPTALDH1A1L3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7981928 | 0.78 | ALDH1A1 (0.36) | LMNAALDH1A1TSHRL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |