Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.52 |
| ▸ | S100A4 | P26447 | 2/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 3/20 | 0.41 |
| ▸ | USP47 | Q96K76 | 3/20 | 0.41 |
| ▸ | USP8 | P40818 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31696105 | 1.00 | PTGES (0.52) | PTGESS100A4PTPRCBCL2MCL1 | |
| SCHEMBL7998365 | 0.84 | USP7 (0.59) | PTGESUSP7USP47USP8MEN1 | |
| SCHEMBL31696139 | 0.81 | USP7 (0.59) | PTGESUSP7USP47USP8MEN1 | |
| SCHEMBL29432454 | 0.78 | RAB9A (0.60) | PTGESPTPRCUSP7USP47USP8 | |
| SCHEMBL7984580 | 0.78 | RAB9A (0.60) | PTGESPTPRCUSP7USP47USP8 | |
| SCHEMBL24873135 | 0.74 | USP7 (0.72) | S100A4PTPRCBCL2MCL1USP7 | |
| SCHEMBL7996571 | 0.71 | USP8 (0.59) | PTGESMCL1USP7USP8MEN1 | |
| SCHEMBL7996577 | 0.71 | PTGES (0.49) | PTGESUSP7USP8MEN1LMNA | |
| SCHEMBL7994964 | 0.70 | PTGES (0.45) | PTGESUSP7USP47USP8MEN1 | |
| SCHEMBL7984594 | 0.68 | PTGES (0.49) | PTGESUSP7USP8MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |