Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 4/20 | 0.59 |
| ▸ | USP7 | Q93009 | 2/20 | 0.59 |
| ▸ | PTGES | O14684 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994928 | 0.81 | PTGES (0.42) | USP8USP7PTGESKMT2ALMNA | |
| SCHEMBL7996719 | 0.76 | PTGES (0.64) | USP8USP7PTGESKMT2ALMNA | |
| SCHEMBL7998545 | 0.74 | USP8 (0.59) | USP8USP7PTGESKMT2ALMNA | |
| SCHEMBL1512498 | 0.74 | USP8 (1.00) | USP8USP7KMT2ALMNAMAPT | |
| SCHEMBL29915621 | 0.74 | USP8 (1.00) | USP8USP7KMT2ALMNAMAPT | |
| SCHEMBL7984594 | 0.74 | PTGES (0.49) | USP8USP7PTGESKMT2ALMNA | |
| SCHEMBL7984622 | 0.71 | PTGES (0.52) | USP8USP7PTGESKMT2ALMNA | |
| SCHEMBL7998365 | 0.71 | USP7 (0.59) | USP8USP7PTGESKMT2ALMNA | |
| SCHEMBL31369142 | 0.70 | CA1 (0.56) | USP8USP7KMT2AMAPTMAPK1 | |
| SCHEMBL18048115 | 0.70 | CA1 (0.56) | USP8USP7KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |