Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432454 | 0.76 | RAB9A (0.60) | PTGESMAPK1KMT2AL3MBTL1HTT | |
| SCHEMBL7984580 | 0.76 | RAB9A (0.60) | PTGESMAPK1KMT2AL3MBTL1HTT | |
| SCHEMBL7983849 | 0.72 | PTGES (0.57) | PTGESMAPK1KMT2AL3MBTL1HTT | |
| SCHEMBL7984632 | 0.72 | USP8 (0.60) | PTGESMAPK1KMT2AL3MBTL1HTT | |
| SCHEMBL31696105 | 0.70 | PTGES (0.52) | PTGESMAPK1KMT2AL3MBTL1HTT | |
| SCHEMBL7984622 | 0.70 | PTGES (0.52) | PTGESMAPK1KMT2AL3MBTL1HTT | |
| SCHEMBL6904504 | 0.69 | MAOA (0.52) | MAPK1KMT2AL3MBTL1HTTMEN1 | |
| SCHEMBL15678555 | 0.69 | CA1 (0.52) | MAPK1KMT2AL3MBTL1HTTMEN1 | |
| SCHEMBL7996719 | 0.69 | PTGES (0.64) | PTGESKMT2AHTTMEN1LMNA | |
| SCHEMBL5412322 | 0.67 | MAPT (0.54) | MAPK1KMT2AL3MBTL1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |