Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694858 | 0.80 | CA1 (0.42) | MAPTKDM4EMCL1MAPK1RAB9A | |
| SCHEMBL4587611 | 0.79 | ALDH1A1 (0.53) | MAPTKDM4EMAPK1RAB9ANPSR1 | |
| SCHEMBL357981 | 0.78 | CA2 (0.53) | MAPTKDM4EMCL1MAPK1RAB9A | |
| SCHEMBL29442958 | 0.78 | CA2 (0.53) | MAPTKDM4EMCL1MAPK1RAB9A | |
| SCHEMBL4308337 | 0.77 | KDM4E (0.49) | MAPTKDM4EMAPK1NPSR1HTT | |
| Formaldehyde SCHEMBL29155314 | 0.77 | CA2 (0.45) | MAPTKDM4EMCL1MAPK1RAB9A | |
| SCHEMBL11132870 | 0.73 | MAOA (0.47) | MAPTKDM4ERAB9AALDH1A1TDP1 | |
| SCHEMBL8525301 | 0.73 | MAOA (0.51) | MAPTKDM4EMCL1RAB9AMEN1 | |
| SCHEMBL11808700 | 0.72 | IDO1 (0.54) | MAPTKDM4EMAPK1RAB9ANPSR1 | |
| SCHEMBL12940963 | 0.72 | MAPT (0.48) | MAPTKDM4EMCL1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |