Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987668 | 0.89 | HDAC8 (0.58) | HDAC8HDAC6SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL7984974 | 0.83 | L3MBTL1 (0.59) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL280256 | 0.83 | HDAC8 (0.68) | HDAC8HDAC6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7983817 | 0.82 | FLT1 (0.61) | MEN1KMT2AKCNK3KCNK9CA1 | |
| SCHEMBL29659751 | 0.82 | HDAC1 (0.62) | HDAC6SMN1; SMN2MEN1KMT2AKCNK3 | |
| SCHEMBL7983790 | 0.82 | HDAC1 (0.62) | HDAC6SMN1; SMN2MEN1KMT2AKCNK3 | |
| SCHEMBL9302340 | 0.82 | KDM4E (0.57) | HDAC8HDAC6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1370670 | 0.80 | LMNA (0.54) | HDAC8HDAC6MEN1KMT2AKAT6A | |
| SCHEMBL7986975 | 0.80 | NPC1 (0.59) | SMN1; SMN2TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL7990728 | 0.79 | HDAC1 (0.59) | HDAC6SMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |