Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680592 | 0.90 | MMP13 (0.61) | HDAC1HDAC6ALDH1A1GAANPC1 | |
| SCHEMBL7984813 | 0.87 | HDAC1 (0.53) | HDAC1HDAC6ALDH1A1GAANPC1 | |
| SCHEMBL24052290 | 0.85 | HDAC8 (0.59) | HDAC6LMNASMN1; SMN2HTT | |
| SCHEMBL7987132 | 0.83 | ALDH1A1 (0.50) | HDAC1ALDH1A1GAARAB9APTGS2 | |
| SCHEMBL7984827 | 0.83 | FLT1 (0.61) | HDAC1ALDH1A1GAANPC1PTGS2 | |
| SCHEMBL7990884 | 0.83 | OGG1 (0.55) | HDAC1HDAC6ALDH1A1NPC1RAB9A | |
| SCHEMBL24052028 | 0.83 | PARP10 (0.46) | HDAC6ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL24420690 | 0.83 | LMNA (0.51) | HDAC1HDAC6ALDH1A1GAANPC1 | |
| SCHEMBL7987067 | 0.83 | PLK1 (0.61) | HDAC6ALDH1A1GAANPC1RAB9A | |
| SCHEMBL1370670 | 0.82 | LMNA (0.54) | HDAC1HDAC6ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118647372-A | Liquid resin extended release oral naltrexone formulations for the treatment of autism related disorders | 阿达瓦克治疗公司 | 2024-09-13 | — | — | CN | disclosed |
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |