Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086603 | 0.84 | — | — | |
| SCHEMBL12938146 | 0.72 | NOS3 (0.33) | — | |
| SCHEMBL798458 | 0.69 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| SCHEMBL14925513 | 0.67 | GAA (0.34) | — | |
| SCHEMBL18237746 | 0.67 | GAA (0.34) | — | |
| SCHEMBL18237707 | 0.66 | PARP1 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL19130948 | 0.66 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL13072278 | 0.65 | PDK1 (0.35) | — | |
| SCHEMBL23231148 | 0.64 | CHRM5 (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL25098212 | 0.63 | CHRNB2 (0.34) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | MTOR, STAT3, SLC14A1 | CHRNB2 4863/4885CHRNA4 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.