Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GUSB | P08236 | 4/20 | 0.51 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.43 |
| ▸ | PARN | O95453 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988556 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HPGDKMT2AGUSB | |
| SCHEMBL7985332 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2ACNOT7 | |
| SCHEMBL7988785 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDKMT2ACNOT7 | |
| SCHEMBL7975265 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HPGDKMT2ACNOT7 | |
| SCHEMBL7975129 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HPGDKMT2ACNOT7 | |
| SCHEMBL7984453 | 0.84 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1HPGDKMT2AGUSB | |
| SCHEMBL7984883 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1HPGDKMT2ACNOT7 | |
| SCHEMBL7974010 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HPGDKMT2ACNOT7 | |
| SCHEMBL7984655 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HPGDKMT2ACNOT7 | |
| SCHEMBL7974505 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2ACNOT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |