Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 4/20 | 0.46 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.46 |
| ▸ | PARN | O95453 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974850 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL7974644 | 0.86 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL7975265 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HPGDKMT2ACNOT7 | |
| SCHEMBL7988556 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HPGDKMT2AGUSB | |
| SCHEMBL7984948 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2AGUSB | |
| SCHEMBL7975119 | 0.83 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1HPGDKMT2AGUSB | |
| SCHEMBL7988785 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDKMT2ACNOT7 | |
| SCHEMBL7985543 | 0.81 | CNOT7 (0.54) | SMN1; SMN2ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL7985798 | 0.81 | GUSB (0.53) | SMN1; SMN2ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL7985332 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2ACNOT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |