Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 6/20 | 0.51 |
| ▸ | PARN | O95453 | 1/20 | 0.51 |
| ▸ | GUSB | P08236 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988562 | 0.88 | CNOT7 (0.54) | CNOT7PARNGUSBALDH1A1SMN1; SMN2 | |
| SCHEMBL7985342 | 0.87 | CNOT7 (0.51) | CNOT7PARNALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7988790 | 0.87 | CNOT7 (0.53) | CNOT7PARNALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7975271 | 0.86 | CNOT7 (0.56) | CNOT7PARNALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7984461 | 0.84 | CNOT7 (0.52) | CNOT7PARNGUSBALDH1A1SMN1; SMN2 | |
| SCHEMBL7975135 | 0.84 | CNOT7 (0.52) | CNOT7PARNALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7984891 | 0.84 | CNOT7 (0.50) | CNOT7PARNALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7984663 | 0.83 | CNOT7 (0.49) | CNOT7PARNALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7974015 | 0.83 | PARN (0.49) | CNOT7PARNALDH1A1SMN1; SMN2PNP | |
| SCHEMBL7974508 | 0.83 | CNOT7 (0.51) | CNOT7PARNALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |