Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983580 | 0.89 | HDAC1 (0.43) | HDAC1EPHX2NR1H4RAB9AALDH1A1 | |
| SCHEMBL7990828 | 0.84 | HDAC1 (0.50) | HDAC1EPHX2NR1H4RAB9AALDH1A1 | |
| SCHEMBL7990725 | 0.80 | ALDH1A1 (0.45) | HDAC1RAB9AALDH1A1NPC1MAPT | |
| SCHEMBL7987064 | 0.79 | ALDH1A1 (0.52) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL7990882 | 0.79 | HTT (0.46) | HDAC1ALDH1A1MAPTHDAC3HDAC2 | |
| SCHEMBL7987131 | 0.79 | HTR7 (0.44) | HDAC1RAB9AALDH1A1NPC1HDAC3 | |
| SCHEMBL7984824 | 0.79 | HTT (0.46) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL6316440 | 0.78 | NPSR1 (0.55) | RAB9AALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL7973511 | 0.76 | USP5 (0.45) | RAB9AALDH1A1NPC1MAPTLMNA | |
| SCHEMBL7983730 | 0.76 | CES2 (0.50) | HDAC1MAPTHDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |