Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HNF4A | P41235 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1135597 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPRT1CTSBTDP1TSHR | |
| Nitric Acid SCHEMBL4385055 | 0.95 | ALDH1A1 (0.55) | ALDH1A1HPRT1CTSBTDP1TSHR | |
| Nitrous Acid SCHEMBL1613758 | 0.93 | ALDH1A1 (0.53) | ALDH1A1HPRT1CTSBTDP1TSHR | |
| Nitrous Acid SCHEMBL6927483 | 0.93 | ALDH1A1 (0.53) | ALDH1A1HPRT1CTSBTDP1TSHR | |
| SCHEMBL28375108 | 0.84 | CYP3A4 (0.50) | ALDH1A1HPRT1CTSBTDP1TSHR | |
| SCHEMBL23499978 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HPRT1CTSBTDP1TSHR | |
| SCHEMBL3065809 | 0.79 | CASP6 (0.59) | ALDH1A1HPRT1CTSBTDP1TSHR | |
| SCHEMBL16204105 | 0.79 | TDP1 (0.50) | ALDH1A1CTSBTDP1TSHRCYP3A4 | |
| SCHEMBL187452 | 0.78 | TSHR (0.65) | ALDH1A1HPRT1CTSBTDP1TSHR | |
| SCHEMBL1645671 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HPRT1CTSBTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250339388-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | MAXYMUNE THERAPEUTICS INC (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250319046-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | MAXYMUNE THERAPEUTICS INC (US) | 2025-10-16 | — | — | US | disclosed |
| US-12427124-B1 | Phenylalanine-based LAT1 inhibitors and uses thereof | Maxymune Therapeutics, Inc. (US) | 2025-09-30 | — | — | US | disclosed |
| US-6271236-B1 | PHENYL UREAS/THIOUREAS AS INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE ENZYME, USEFUL IN TREATING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, AND VARICELLA-ZOSTER VIRUS | WYETH | 2001-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250339388-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | SLC43A1, SLC7A1, SLC1A5 | ALDH1A1 2745/4885HPRT1 248/4885CTSB 1883/4885 |
| US-12427124-B1 | Phenylalanine-based LAT1 inhibitors and uses thereof | SLC43A1, SLC7A1, SLC1A5 | ALDH1A1 2745/4885HPRT1 248/4885CTSB 1883/4885 |
| US-20250319046-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | SLC43A1, SLC7A1, SLC1A5 | ALDH1A1 2745/4885HPRT1 248/4885CTSB 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.