Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974268 | 0.91 | CYP11B1 (0.48) | LMNAALDH1A1CYP11B1CYP11B2ADORA2A | |
| SCHEMBL7991557 | 0.90 | LMNA (0.43) | LMNAALDH1A1CYP11B1CYP11B2ADORA2A | |
| SCHEMBL7988567 | 0.90 | HPGD (0.44) | LMNAALDH1A1CYP11B1CYP11B2ADORA2A | |
| SCHEMBL7988747 | 0.89 | CYP11B1 (0.44) | LMNAALDH1A1CYP11B1CYP11B2ADORA2A | |
| SCHEMBL7974247 | 0.87 | CYP11B1 (0.44) | LMNAALDH1A1CYP11B1CYP11B2ADORA2A | |
| SCHEMBL7985060 | 0.86 | ADORA2A (0.39) | LMNACYP11B1CYP11B2ADORA2AHPGD | |
| SCHEMBL7975133 | 0.86 | ADORA2A (0.50) | ALDH1A1CYP11B1CYP11B2ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL7985515 | 0.85 | ADORA2A (0.49) | ALDH1A1CYP11B1CYP11B2ADORA2AADORA1 | |
| SCHEMBL7975240 | 0.85 | ALDH1A1 (0.42) | LMNAALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL7988958 | 0.85 | ALDH1A1 (0.42) | LMNAALDH1A1CYP11B1CYP11B2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |