Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | LATS1 | O95835 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974268 | 0.91 | CYP11B1 (0.48) | CYP11B1CYP11B2ALDH1A1LMNAHPGD | |
| SCHEMBL7985236 | 0.89 | LMNA (0.44) | CYP11B1CYP11B2ALDH1A1LMNAHPGD | |
| SCHEMBL7988934 | 0.89 | CYP1A2 (0.47) | CYP11B1CYP11B2ALDH1A1LMNAHPGD | |
| SCHEMBL7988567 | 0.88 | HPGD (0.44) | CYP11B1CYP11B2ALDH1A1LMNAHPGD | |
| SCHEMBL7974247 | 0.87 | CYP11B1 (0.44) | CYP11B1CYP11B2ALDH1A1LMNAHPGD | |
| SCHEMBL7974267 | 0.87 | SMN1; SMN2 (0.43) | CYP11B1CYP11B2HPGDHTTSMN1; SMN2 | |
| SCHEMBL7985264 | 0.87 | CYP11B1 (0.41) | CYP11B1CYP11B2ALDH1A1LMNAHPGD | |
| SCHEMBL7985826 | 0.86 | NPC1 (0.41) | CYP11B1CYP11B2ALDH1A1LMNAHPGD | |
| SCHEMBL7989313 | 0.86 | ROCK2 (0.52) | ROCK2ROCK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7974441 | 0.86 | GRK2 (0.43) | CYP11B1CYP11B2ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |