Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MASP2 | O00187 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988847 | 0.92 | RAB9A (0.43) | SMN1; SMN2ALDH1A1MAPK1HPGDMASP2 | |
| SCHEMBL7991993 | 0.89 | DGAT1 (0.36) | SMN1; SMN2ALDH1A1MAPK1HPGDMASP2 | |
| SCHEMBL7975249 | 0.85 | HRH3 (0.30) | — | |
| SCHEMBL7992134 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1MAPK1HPGDMASP2 | |
| SCHEMBL7987416 | 0.81 | — | — | |
| SCHEMBL7986497 | 0.80 | POLB (0.42) | SMN1; SMN2MASP2LMNASLC6A2TDP1 | |
| SCHEMBL7969069 | 0.79 | LMNA (0.53) | SMN1; SMN2ALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL7985722 | 0.78 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1MAPK1LMNATSHR | |
| SCHEMBL7992358 | 0.75 | HPGD (0.44) | SMN1; SMN2ALDH1A1MAPK1HPGDMASP2 | |
| SCHEMBL7975316 | 0.75 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1MAPK1HPGDMASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |