Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973841 | 0.95 | RAB9A (0.47) | ALDH1A1RAB9ANPC1IDO1RXFP1 | |
| SCHEMBL7975241 | 0.92 | GAA (0.50) | RAB9ANPC1RXFP1POLBGAA | |
| SCHEMBL7988029 | 0.90 | IDO1 (0.47) | RAB9ANPC1IDO1RXFP1POLB | |
| SCHEMBL7985361 | 0.89 | P2RY14 (0.52) | ALDH1A1CNR2KDM4ECDK2HDAC1 | |
| SCHEMBL7988506 | 0.88 | NTRK1 (0.48) | ALDH1A1RAB9ANPC1IDO1KDM4E | |
| SCHEMBL7984200 | 0.88 | SMN1; SMN2 (0.53) | ALDH1A1RAB9ANPC1PKMTSHR | |
| SCHEMBL7986413 | 0.88 | HTT (0.52) | ALDH1A1RAB9ATSHRHDAC1HDAC6 | |
| SCHEMBL7985682 | 0.87 | GAA (0.46) | ALDH1A1RAB9ARXFP1POLBGAA | |
| SCHEMBL7973823 | 0.87 | NPC1 (0.48) | ALDH1A1RAB9ANPC1IDO1RXFP1 | |
| SCHEMBL7991372 | 0.87 | NR1H4 (0.49) | ALDH1A1HDAC1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |