Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975241 | 0.93 | GAA (0.50) | GAAPKMTSHRSMN1; SMN2RAB9A | |
| SCHEMBL7986413 | 0.89 | HTT (0.52) | TSHRHTTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7988029 | 0.88 | IDO1 (0.47) | GAAPKMTSHRSMN1; SMN2RAB9A | |
| SCHEMBL7985255 | 0.87 | ALDH1A1 (0.51) | GAAPKMTSHRHTTSMN1; SMN2 | |
| SCHEMBL7985500 | 0.87 | NR1H4 (0.48) | SMN1; SMN2KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL7974581 | 0.86 | LMNA (0.51) | GAAPKMTSHRHTTSMN1; SMN2 | |
| SCHEMBL7985506 | 0.86 | GAA (0.48) | GAAPKMTSHRHTTSMN1; SMN2 | |
| SCHEMBL7984668 | 0.85 | POLB (0.49) | SMN1; SMN2KDM4EMAPTRAB9APOLB | |
| SCHEMBL7973841 | 0.85 | RAB9A (0.47) | GAAPKMTSHRRAB9AMEN1 | |
| SCHEMBL7974040 | 0.84 | KDM4E (0.51) | GAAPKMTSHRKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |