Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974581 | 0.93 | LMNA (0.51) | GAAPKMTSHRFLT3POLB | |
| SCHEMBL7985682 | 0.93 | GAA (0.46) | GAAPKMTSHRPOLBRXFP1 | |
| SCHEMBL7988029 | 0.93 | IDO1 (0.47) | GAAPKMTSHRFLT3POLB | |
| SCHEMBL7973841 | 0.92 | RAB9A (0.47) | GAAPKMTSHRRXFP1HSD17B13 | |
| SCHEMBL7985255 | 0.92 | ALDH1A1 (0.51) | GAAPKMTSHRFLT3POLB | |
| SCHEMBL7974040 | 0.91 | KDM4E (0.51) | GAAPKMTSHRHSD17B13ADORA3 | |
| SCHEMBL7984694 | 0.90 | NR1H4 (0.53) | GAAPKMTSHRRXFP1HDAC1 | |
| SCHEMBL7984492 | 0.90 | ADORA2A (0.53) | FLT3ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7984668 | 0.90 | POLB (0.49) | POLBADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7985033 | 0.89 | NLRP3 (0.46) | POLBADORA3YTHDC1NTRK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |