Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | DHPS | P49366 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974289 | 0.90 | CNOT7 (0.53) | CNOT7SMN1; SMN2PARNDHPSCLK1 | |
| SCHEMBL7984771 | 0.90 | CNOT7 (0.47) | CNOT7SMN1; SMN2GRIN1GRIN2BPARN | |
| SCHEMBL7985337 | 0.89 | CNOT7 (0.48) | CNOT7CYP11B1GRIN1GRIN2BCLK1 | |
| SCHEMBL7986522 | 0.88 | CNOT7 (0.48) | CNOT7SMN1; SMN2CYP11B1CYP11B2PARN | |
| SCHEMBL7985279 | 0.87 | CNOT7 (0.49) | CNOT7SMN1; SMN2PARNDYRK1AHTT | |
| SCHEMBL7974239 | 0.87 | CNOT7 (0.45) | CNOT7PARNDHPSCLK1DYRK1A | |
| SCHEMBL7984283 | 0.87 | CNOT7 (0.43) | CNOT7SMN1; SMN2PKMCYP11B2PARN | |
| SCHEMBL7988736 | 0.85 | ACP1 (0.45) | CNOT7SMN1; SMN2CYP11B1CYP11B2GRIN1 | |
| SCHEMBL7988666 | 0.85 | CNOT7 (0.48) | CNOT7SMN1; SMN2GRIN1GRIN2BPARN | |
| SCHEMBL7985119 | 0.84 | CNOT7 (0.42) | CNOT7SMN1; SMN2HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |