Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988644 | 0.92 | GRIN1 (0.42) | CNOT7ROCK2ROCK1GRIN1GRIN2B | |
| SCHEMBL7985794 | 0.92 | PARN (0.46) | CNOT7ROCK2ROCK1GRIN1GRIN2B | |
| SCHEMBL7991676 | 0.90 | ACP1 (0.43) | CNOT7ROCK2ROCK1GRIN1GRIN2B | |
| SCHEMBL7985337 | 0.89 | CNOT7 (0.48) | CNOT7ROCK2ROCK1GRIN1GRIN2B | |
| SCHEMBL8056886 | 0.88 | SMN1; SMN2 (0.46) | CNOT7MAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL7988751 | 0.88 | CNOT7 (0.43) | CNOT7ROCK2ROCK1GRIN1GRIN2B | |
| SCHEMBL7985279 | 0.87 | CNOT7 (0.49) | CNOT7MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7974444 | 0.87 | CNOT7 (0.52) | CNOT7KDM4EPARNADORA2BGRK2 | |
| SCHEMBL7985302 | 0.87 | ROCK2 (0.41) | CNOT7ROCK2ROCK1GRIN1GRIN2B | |
| SCHEMBL7985362 | 0.86 | GRIN1 (0.45) | CNOT7GRIN1GRIN2BPARNMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |