Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985287 | 0.85 | CNOT7 (0.40) | ALDH1A1KMT2AMEN1PDE4AADORA2A | |
| SCHEMBL7988249 | 0.83 | PDE5A (0.50) | ALDH1A1KMT2AMEN1PDE4AADORA2A | |
| SCHEMBL7985781 | 0.81 | MEN1 (0.46) | ALDH1A1KMT2AMEN1PDE4AADORA2A | |
| SCHEMBL7985373 | 0.80 | PDE5A (0.49) | ALDH1A1KMT2AMEN1PDE4AADORA2A | |
| SCHEMBL7985284 | 0.79 | TLR4 (0.35) | ALDH1A1LMNAPOLBHPGDNPSR1 | |
| SCHEMBL7984961 | 0.79 | HPGD (0.48) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL7974064 | 0.79 | XDH (0.48) | ALDH1A1KMT2AMEN1PDE4AADORA2A | |
| SCHEMBL7984998 | 0.76 | PDE5A (0.52) | ALDH1A1KMT2AMEN1PDE4AADORA2A | |
| SCHEMBL7987442 | 0.76 | HPGD (0.46) | ALDH1A1KMT2AMEN1HPGDXBP1 | |
| SCHEMBL7985069 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1KMT2AMEN1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |