Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | TLR3 | O15455 | 1/20 | 0.35 |
| ▸ | TLR5 | O60602 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.35 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.35 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.35 |
| ▸ | CAMK4 | Q16566 | 1/20 | 0.35 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.35 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.35 |
| ▸ | CAMK1G | Q96NX5 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985784 | 0.82 | LMNA (0.40) | HPGDLMNAALDH1A1GAAPOLB | |
| SCHEMBL7988251 | 0.82 | NR1H3 (0.43) | TLR8HPGDCNOT7NPC1ALDH1A1 | |
| SCHEMBL7985282 | 0.79 | ALDH1A1 (0.41) | HPGDLMNAALDH1A1NPSR1POLB | |
| SCHEMBL7985379 | 0.79 | TLR8 (0.44) | TLR8HPGDCNOT7NPC1ALDH1A1 | |
| SCHEMBL7984968 | 0.78 | GAA (0.40) | TLR7HPGDLMNAALDH1A1NR1H3 | |
| SCHEMBL7974065 | 0.78 | TLR8 (0.43) | TLR8HPGDCNOT7NPC1ALDH1A1 | |
| SCHEMBL7984888 | 0.76 | HPGD (0.41) | HPGDLMNACNOT7ALDH1A1GAA | |
| SCHEMBL7987443 | 0.75 | GAA (0.37) | TLR7HPGDLMNANPC1ALDH1A1 | |
| SCHEMBL7985000 | 0.75 | ADORA2A (0.40) | TLR9NR1H3 | |
| SCHEMBL7985071 | 0.75 | BCL2L2 (0.39) | HPGDLMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |