Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | TPO | P07202 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558251 | 0.79 | TAAR1 (0.43) | MPOTPODPP4F2HTR2A | |
| Hydrochloric Acid SCHEMBL8865240 | 0.77 | TAAR1 (0.41) | MPOTPODPP4F2HTR2A | |
| SCHEMBL8958232 | 0.77 | OPRM1 (0.42) | MPOTPODPP4F2HTR2A | |
| SCHEMBL9719141 | 0.75 | DPP4 (0.55) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL17871883 | 0.73 | SLC6A4 (0.48) | TDP1HTR2AKDM4E | |
| SCHEMBL8555524 | 0.73 | HTR2A (0.40) | MPOTPODPP4F2HTR2A | |
| SCHEMBL10900322 | 0.73 | MEN1 (0.38) | TDP1LMNA | |
| SCHEMBL6055136 | 0.72 | GABRA1 (0.48) | TDP1LMNAHIF1A | |
| SCHEMBL30606846 | 0.72 | GABRA1 (0.48) | TDP1LMNAHIF1A | |
| Hydrochloric Acid SCHEMBL8596089 | 0.71 | CYP3A4 (0.42) | MPOTPOHTR2ATAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |