Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.36 |
| ▸ | PARN | O95453 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984380 | 0.83 | CYP11B1 (0.40) | ALDH1A1KDM4EMAPTCNOT7PARN | |
| SCHEMBL7985527 | 0.83 | HPGD (0.41) | TDP1ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL7992340 | 0.82 | CNOT7 (0.40) | ALDH1A1CNOT7PARNKMT2AMEN1 | |
| SCHEMBL7984470 | 0.81 | ABCC8 (0.50) | TDP1CNOT7PARNKMT2AMEN1 | |
| SCHEMBL7988132 | 0.81 | CNOT7 (0.44) | ALDH1A1CNOT7PARNMAPK1LMNA | |
| SCHEMBL7975254 | 0.78 | CNOT7 (0.55) | ALDH1A1CNOT7PARNKMT2AHIF1A | |
| SCHEMBL7986239 | 0.77 | CNOT7 (0.47) | ALDH1A1CNOT7PARNKMT2AMEN1 | |
| SCHEMBL7987439 | 0.77 | CNOT7 (0.43) | ALDH1A1KDM4EMAPTCNOT7PARN | |
| SCHEMBL7985247 | 0.77 | HSP90AA1 (0.45) | KDM4EKMT2AMEN1LMNA | |
| SCHEMBL7984530 | 0.76 | HPGD (0.46) | ALDH1A1KDM4ECNOT7PARNKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |