Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.32 |
| ▸ | GRK1 | Q15835 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987444 | 0.88 | PARN (0.42) | CNOT7PARNSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7992335 | 0.85 | HPGD (0.44) | CNOT7PARNSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7975254 | 0.83 | CNOT7 (0.55) | CNOT7PARNSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7987785 | 0.82 | PARN (0.47) | CNOT7PARNSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7985523 | 0.82 | TDP1 (0.39) | CNOT7PARNHPGDALDH1A1HTT | |
| SCHEMBL7984470 | 0.77 | ABCC8 (0.50) | CNOT7PARNSMN1; SMN2HPGDMEN1 | |
| SCHEMBL7973938 | 0.77 | CNOT7 (0.48) | CNOT7PARNSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7985476 | 0.77 | CNOT7 (0.53) | CNOT7PARNSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7984380 | 0.76 | CYP11B1 (0.40) | CNOT7PARNSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7985654 | 0.76 | CNOT7 (0.42) | CNOT7PARNSMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |