Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793893 | 0.81 | CYP11B2 (0.37) | — | |
| SCHEMBL792837 | 0.78 | CYP17A1 (0.48) | CYP17A1 | |
| SCHEMBL793437 | 0.77 | CYP17A1 (0.50) | CYP17A1 | |
| SCHEMBL27901812 | 0.76 | CYP17A1 (0.42) | CYP17A1 | |
| SCHEMBL793474 | 0.71 | CYP11B2 (0.41) | CYP17A1 | |
| SCHEMBL793317 | 0.69 | CYP11B1 (0.57) | CYP17A1 | |
| SCHEMBL27919592 | 0.68 | CYP17A1 (0.43) | CYP17A1 | |
| SCHEMBL794363 | 0.66 | CYP17A1 (0.53) | CYP17A1 | |
| SCHEMBL9192064 | 0.66 | EED (0.62) | — | |
| SCHEMBL10286388 | 0.65 | CYP17A1 (0.45) | CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627648-A1 | 17aHYDROXYLASE/C17,20-LYASE INHIBITORS | Novartis AG (CH) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012035078-A1 | 17α-HYDROXYLASE/C17,20-LYASE INHIBITORS | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |