Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 14/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793875 | 0.82 | TRPV3 (0.41) | HTR2AHTR2C | |
| SCHEMBL794272 | 0.78 | PHGDH (0.43) | HTR2AHTR2C | |
| SCHEMBL798567 | 0.77 | CYP17A1 (0.44) | CYP17A1 | |
| SCHEMBL793796 | 0.77 | CYP17A1 (0.58) | CYP17A1 | |
| SCHEMBL20776824 | 0.70 | MAPT (0.46) | — | |
| SCHEMBL798794 | 0.68 | HRH3 (0.40) | HTR2AHTR2C | |
| SCHEMBL12065737 | 0.68 | TRPV3 (0.39) | CCR2 | |
| SCHEMBL13735785 | 0.67 | CYP17A1 (1.00) | CYP17A1 | |
| SCHEMBL13737172 | 0.67 | CYP17A1 (1.00) | CYP17A1 | |
| SCHEMBL10078849 | 0.66 | MAOA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627648-A1 | 17aHYDROXYLASE/C17,20-LYASE INHIBITORS | Novartis AG (CH) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012035078-A1 | 17α-HYDROXYLASE/C17,20-LYASE INHIBITORS | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |