Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989719 | 1.00 | LMNA (0.42) | LMNARAB9ACA12CA1CA7 | |
| SCHEMBL7986750 | 0.88 | MMP8 (0.48) | LMNARAB9ACA12CA1CA7 | |
| SCHEMBL7986748 | 0.88 | MMP8 (0.48) | LMNARAB9ACA12CA1CA7 | |
| SCHEMBL7992662 | 0.82 | SMN1; SMN2 (0.56) | LMNARAB9AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL7992658 | 0.82 | SMN1; SMN2 (0.56) | LMNARAB9AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL7985676 | 0.79 | MAPT (0.31) | MAPT | |
| SCHEMBL7985674 | 0.79 | MAPT (0.31) | MAPT | |
| SCHEMBL7985945 | 0.77 | MAPT (0.35) | RAB9ACTSKSMN1; SMN2MAPTMEN1 | |
| SCHEMBL7985951 | 0.77 | MAPT (0.35) | RAB9ACTSKSMN1; SMN2MAPTMEN1 | |
| SCHEMBL7988109 | 0.77 | GRIN2D (0.49) | LMNARAB9ACA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |