Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | TPH1 | P17752 | 1/20 | 0.42 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985859 | 0.83 | CNOT7 (0.49) | SMN1; SMN2ALDH1A1KMT2AHPGDCNOT7 | |
| SCHEMBL7974283 | 0.82 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDCNOT7 | |
| SCHEMBL7985687 | 0.82 | CNOT7 (0.55) | SMN1; SMN2ALDH1A1KMT2AHPGDCNOT7 | |
| SCHEMBL7985469 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1KMT2AHPGDCNOT7 | |
| SCHEMBL7975251 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1KMT2AHPGDCNOT7 | |
| SCHEMBL7988094 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1KMT2AHPGDCNOT7 | |
| SCHEMBL7984363 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KMT2AHPGDCNOT7 | |
| SCHEMBL7974513 | 0.81 | ADORA3 (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL7987463 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KMT2AHPGDCNOT7 | |
| Hydrochloric Acid SCHEMBL7992062 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KMT2AHPGDCNOT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |