Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 7/20 | 0.50 |
| ▸ | PARN | O95453 | 1/20 | 0.48 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974857 | 0.89 | CNOT7 (0.52) | CXCR2PARNCNOT7GUSBP2RX7 | |
| SCHEMBL7984461 | 0.84 | CNOT7 (0.52) | CXCR2PARNCNOT7GUSBPNP | |
| SCHEMBL7974015 | 0.83 | PARN (0.49) | CXCR2PARNCNOT7PNPALDH1A1 | |
| SCHEMBL7985798 | 0.83 | GUSB (0.53) | CXCR2PARNCNOT7GUSBP2RX7 | |
| SCHEMBL7988669 | 0.83 | PARN (0.48) | CXCR2PARNCNOT7P2RX7PNP | |
| SCHEMBL7991406 | 0.82 | CNOT7 (0.49) | CXCR2PARNCNOT7GUSBPNP | |
| SCHEMBL7985428 | 0.82 | SMN1; SMN2 (0.41) | PARNCNOT7P2RX7ALDH1A1SMN1; SMN2 | |
| SCHEMBL7975271 | 0.81 | CNOT7 (0.56) | CXCR2PARNCNOT7PNPALDH1A1 | |
| SCHEMBL7984880 | 0.81 | P2RX7 (0.46) | CXCR2PARNCNOT7P2RX7SMN1; SMN2 | |
| SCHEMBL7985543 | 0.81 | CNOT7 (0.54) | PARNCNOT7GUSBPNPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |