Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.49 |
| ▸ | PARN | O95453 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984461 | 0.95 | CNOT7 (0.52) | CNOT7PARNSMN1; SMN2KMT2APNP | |
| SCHEMBL7975271 | 0.93 | CNOT7 (0.56) | CNOT7PARNSMN1; SMN2KMT2APNP | |
| SCHEMBL7986522 | 0.89 | CNOT7 (0.48) | CNOT7PARNCYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL7984720 | 0.89 | CNOT7 (0.48) | CNOT7PARNCYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL7988669 | 0.89 | PARN (0.48) | CNOT7PARNSMN1; SMN2MAPK1HTT | |
| SCHEMBL7974015 | 0.87 | PARN (0.49) | CNOT7PARNSMN1; SMN2MAPK1HTT | |
| SCHEMBL7974492 | 0.86 | ABCC8 (0.47) | CNOT7PARNSMN1; SMN2HTTMEN1 | |
| SCHEMBL7985707 | 0.86 | CYP11B2 (0.47) | CNOT7PARNCYP11B1CYP11B2HTT | |
| SCHEMBL7987953 | 0.86 | PDE2A (0.46) | CNOT7PARNSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7974444 | 0.86 | CNOT7 (0.52) | CNOT7PARNSMN1; SMN2KMT2APNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |