Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989411 | 0.88 | CNOT7 (0.53) | CNOT7HPGDSMN1; SMN2POLBPARN | |
| SCHEMBL7974259 | 0.86 | CNOT7 (0.54) | CNOT7KDM4EL3MBTL1HPGDHSD17B10 | |
| SCHEMBL7985687 | 0.83 | CNOT7 (0.55) | CNOT7KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL7985859 | 0.83 | CNOT7 (0.49) | CNOT7KDM4EL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL7988665 | 0.83 | ALDH1A1 (0.44) | CNOT7HPGDSMN1; SMN2LMNAHTT | |
| SCHEMBL7989379 | 0.82 | CNOT7 (0.41) | CNOT7KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL7988487 | 0.82 | PDE1A (0.46) | CNOT7KDM4EHPGDLMNAPARN | |
| SCHEMBL7991727 | 0.82 | SMN1; SMN2 (0.49) | CNOT7L3MBTL1SMN1; SMN2HTTPARN | |
| SCHEMBL7988961 | 0.81 | KDM4E (0.42) | CNOT7KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL7987612 | 0.81 | CNOT7 (0.51) | CNOT7HPGDSMN1; SMN2POLBPARN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |