Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.41 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987439 | 0.90 | CNOT7 (0.43) | CNOT7PARNLMNACYP11B1CYP11B2 | |
| SCHEMBL7975139 | 0.89 | CNOT7 (0.40) | CNOT7PARNLMNACYP11B1CYP11B2 | |
| SCHEMBL7988961 | 0.89 | KDM4E (0.42) | CNOT7PARNLMNACYP11B2HTT | |
| SCHEMBL7989411 | 0.89 | CNOT7 (0.53) | CNOT7PARNSMN1; SMN2BRD4KMT2A | |
| SCHEMBL7974259 | 0.88 | CNOT7 (0.54) | CNOT7PARNKDM4ETLR7HPGD | |
| SCHEMBL7984748 | 0.87 | ABCC8 (0.48) | CNOT7PARNLMNAMEN1KMT2A | |
| SCHEMBL7988665 | 0.86 | ALDH1A1 (0.44) | CNOT7PARNLMNACYP11B1CYP11B2 | |
| SCHEMBL7985736 | 0.86 | YTHDC1 (0.43) | CNOT7PARNSMN1; SMN2TP53MEN1 | |
| SCHEMBL7988039 | 0.86 | CNOT7 (0.41) | CNOT7PARNLMNACYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7988145 | 0.85 | CNOT7 (0.40) | CNOT7PARNLMNACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |