Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.54 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989411 | 0.89 | CNOT7 (0.53) | CNOT7PARNALDH1A1HPGDRXFP1 | |
| SCHEMBL7989379 | 0.88 | CNOT7 (0.41) | CNOT7PARNKDM4EHPGDTLR7 | |
| SCHEMBL7988961 | 0.87 | KDM4E (0.42) | CNOT7PARNKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7985863 | 0.86 | CNOT7 (0.57) | CNOT7PARNKDM4EHSD17B10KDM4C | |
| SCHEMBL7984748 | 0.85 | ABCC8 (0.48) | CNOT7PARNMAPK1 | |
| SCHEMBL7985736 | 0.84 | YTHDC1 (0.43) | CNOT7PARNKDM4EHPGDYTHDC1 | |
| SCHEMBL7991727 | 0.83 | SMN1; SMN2 (0.49) | CNOT7PARNYTHDC1MAPK1L3MBTL1 | |
| SCHEMBL7987612 | 0.82 | CNOT7 (0.51) | CNOT7PARNALDH1A1HPGDRXFP1 | |
| SCHEMBL7988665 | 0.82 | ALDH1A1 (0.44) | CNOT7PARNALDH1A1HPGD | |
| SCHEMBL7989567 | 0.81 | CNOT7 (0.50) | CNOT7PARNALDH1A1HPGDRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |