Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.92 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986224 | 0.96 | SIGMAR1 (1.00) | SIGMAR1FAAHDRD2 | |
| SCHEMBL7971891 | 0.94 | SIGMAR1 (0.80) | SIGMAR1L3MBTL1DRD2 | |
| SCHEMBL7983465 | 0.89 | SIGMAR1 (0.87) | SIGMAR1DRD2 | |
| SCHEMBL7989733 | 0.84 | SIGMAR1 (0.64) | SIGMAR1CHRM3FAAH | |
| SCHEMBL1222005 | 0.82 | SIGMAR1 (0.76) | SIGMAR1 | |
| SCHEMBL7985885 | 0.79 | SIGMAR1 (0.59) | SIGMAR1CHRM3FAAH | |
| SCHEMBL7971782 | 0.79 | SIGMAR1 (0.69) | SIGMAR1FAAH | |
| SCHEMBL8526553 | 0.78 | SIGMAR1 (0.59) | SIGMAR1CHRM3 | |
| SCHEMBL22151422 | 0.78 | SIGMAR1 (0.62) | SIGMAR1DRD2 | |
| SCHEMBL7985958 | 0.78 | SIGMAR1 (0.68) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |