Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.47 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983465 | 0.96 | SIGMAR1 (0.87) | SIGMAR1MEN1KMT2AKCNH2NPFFR1 | |
| SCHEMBL7985879 | 0.94 | SIGMAR1 (0.92) | SIGMAR1L3MBTL1DRD2 | |
| SCHEMBL7986224 | 0.89 | SIGMAR1 (1.00) | SIGMAR1DRD2 | |
| SCHEMBL1222005 | 0.84 | SIGMAR1 (0.76) | SIGMAR1MEN1KMT2ANPFFR1NPFFR2 | |
| SCHEMBL7986044 | 0.83 | SIGMAR1 (0.55) | SIGMAR1ACHEMEN1KMT2AKCNH2 | |
| SCHEMBL7971893 | 0.78 | MEN1 (0.52) | SIGMAR1ACHEMEN1KMT2AKCNH2 | |
| SCHEMBL14691386 | 0.78 | SIGMAR1 (0.66) | SIGMAR1L3MBTL1MEN1KMT2ANPFFR1 | |
| SCHEMBL3712707 | 0.78 | MEN1 (0.59) | SIGMAR1MEN1KMT2AKCNH2POLB | |
| SCHEMBL4075221 | 0.77 | SIGMAR1 (0.57) | SIGMAR1L3MBTL1MEN1KMT2AP2RX7 | |
| SCHEMBL7989733 | 0.77 | SIGMAR1 (0.64) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |