Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.69 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989733 | 0.95 | SIGMAR1 (0.64) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| SCHEMBL3712707 | 0.92 | MEN1 (0.59) | SIGMAR1ACKR3 | |
| SCHEMBL8526553 | 0.91 | SIGMAR1 (0.59) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| SCHEMBL7983371 | 0.89 | GPR119 (0.61) | SIGMAR1 | |
| SCHEMBL31752794 | 0.89 | SIGMAR1 (0.56) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| SCHEMBL1421344 | 0.87 | SIGMAR1 (0.55) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| SCHEMBL15997218 | 0.87 | SIGMAR1 (0.55) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| SCHEMBL7986044 | 0.87 | SIGMAR1 (0.55) | SIGMAR1ACKR3 | |
| SCHEMBL30812306 | 0.87 | SIGMAR1 (0.54) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| SCHEMBL27980806 | 0.87 | SIGMAR1 (0.54) | SIGMAR1HTR2AOPRM1ADORA3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1223659-A | Fused imidazopyridine derivatives as antihyperlipidemic agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-21 | — | — | CN | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |