Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985992 | 1.00 | MEN1 (0.42) | MEN1KMT2AAOC3SLC6A2SLC6A4 | |
| SCHEMBL7975750 | 0.82 | MEN1 (0.41) | MEN1KMT2ASLC6A2SLC6A4TACR1 | |
| SCHEMBL7975749 | 0.82 | MEN1 (0.41) | MEN1KMT2ASLC6A2SLC6A4TACR1 | |
| SCHEMBL7976197 | 0.75 | CYP26A1 (0.37) | MEN1KMT2A | |
| SCHEMBL7976195 | 0.75 | CYP26A1 (0.37) | MEN1KMT2A | |
| SCHEMBL7990370 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL7990372 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL7986448 | 0.68 | METAP2 (0.41) | TACR1TDP1 | |
| SCHEMBL7986441 | 0.68 | METAP2 (0.41) | TACR1TDP1 | |
| SCHEMBL14102623 | 0.68 | KDM4E (0.46) | MEN1KMT2ATACR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |