SCHEMBL7976197 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CYP26A1	O43174	1/20	0.37

▸	MEN1	O00255	1/20	0.36

▸	KMT2A	Q03164	1/20	0.36

▸	MMP2	P08253	14/20	0.36

▸	MMP3	P08254	9/20	0.36

▸	MMP9	P14780	3/20	0.34

▸	MMP1	P03956	2/20	0.34

▸	MMP14	P50281	2/20	0.34

▸	PDF	Q9HBH1	1/20	0.34

▸	CYP2D6	P10635	1/20	0.34

▸	CYP2C9	P11712	1/20	0.34

▸	ALOX15	P16050	1/20	0.34

▸	CYP2C19	P33261	1/20	0.34

▸	FOLH1	Q04609	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7976195	1.00	CYP26A1 (0.37)	CYP26A1MEN1KMT2AMMP2MMP3
SCHEMBL7975750	0.85	MEN1 (0.41)	CYP26A1MEN1KMT2ACYP2D6CYP2C9
SCHEMBL7975749	0.85	MEN1 (0.41)	CYP26A1MEN1KMT2ACYP2D6CYP2C9
SCHEMBL7989538	0.76	PDF (0.43)	MMP2MMP3MMP1PDF
SCHEMBL7986858	0.76	MMP2 (0.46)	MMP2MMP3MMP1
SCHEMBL7986860	0.76	MMP2 (0.38)	MMP2MMP3
SCHEMBL7986859	0.75	MMP9 (0.45)	MMP2MMP3MMP9MMP1MMP14
SCHEMBL7985997	0.75	MEN1 (0.42)	MEN1KMT2A
SCHEMBL7985992	0.75	MEN1 (0.42)	MEN1KMT2A
SCHEMBL7976169	0.74	PDF (0.44)	MMP2MMP3MMP9MMP1MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2001040198-A2	MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS	AVENTIS PHARMA S.A. (FR)	2001-06-07	—	—	WO	disclosed