Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | DRD4 | P21917 | 5/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7983416 | 0.99 | DRD2 (0.34) | DRD2DRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL7982596 | 0.81 | OPRM1 (0.40) | KCNH2 | |
| SCHEMBL7985740 | 0.81 | FNTA (0.36) | DRD2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7983124 | 0.81 | HDAC3 (0.51) | DRD2DRD4HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL7972311 | 0.81 | OPRM1 (0.41) | KCNH2 | |
| Hydrochloric Acid SCHEMBL7986252 | 0.80 | FNTA (0.38) | DRD2HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL7983228 | 0.80 | HDAC3 (0.50) | DRD2DRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL7989641 | 0.79 | SHMT2 (0.42) | LTA4HEPHX2CKS1BSKP1SKP2 | |
| SCHEMBL7986626 | 0.79 | LMNA (0.38) | DRD2DRD4HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL7981882 | 0.78 | SHMT2 (0.41) | KCNH2LTA4HEPHX2CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |