Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969322 | 0.78 | MGAM (0.48) | TSHRMAPTRECQLMAOBESR1 | |
| SCHEMBL8969329 | 0.78 | MGAM (0.48) | TSHRMAPTRECQLMAOBESR1 | |
| SCHEMBL31054141 | 0.69 | MAPT (0.35) | TSHRMAPTALDH1A1ESR1ESR2 | |
| SCHEMBL8002913 | 0.69 | ALDH1A1 (0.32) | TSHRALDH1A1ESR1ESR2 | |
| SCHEMBL5146811 | 0.68 | HCAR2 (0.46) | MAPTALDH1A1RECQL | |
| SCHEMBL6561378 | 0.67 | — | — | |
| SCHEMBL8157734 | 0.67 | MAOB (0.48) | MAPTALDH1A1RECQLMAOB | |
| SCHEMBL7748544 | 0.67 | CA1 (0.44) | MAPTALDH1A1MAOB | |
| SCHEMBL7748547 | 0.67 | CA1 (0.44) | MAPTALDH1A1MAOB | |
| SCHEMBL5595930 | 0.66 | MAPT (0.35) | MAPTESR1ESR2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886638-A4 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2000-12-27 | — | — | EP | disclosed |
| US-6051699-A | Process for the synthesis of oligomeric compounds | ISIS PHARMACEUTICALS, INC. (US) | 2000-04-18 | — | — | US | disclosed |
| US-5859232-A | Process for the synthesis of oligomeric phosphite, phosphodiester, phosphorothioate and phosphorodithioate compounds | ISIS PHARMACEUTICALS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0886638-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1998-12-30 | — | — | EP | disclosed |
| US-5705621-A | Oligomeric phosphite, phosphodiester, Phosphorothioate and phosphorodithioate compounds and intermediates for preparing same | ISIS PHARMACEUTICALS, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| WO-1997019092-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1997-05-29 | — | — | WO | disclosed |