Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31054141 | 0.74 | MAPT (0.35) | ALDH1A1TSHRESR1ESR2 | |
| SCHEMBL226240 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRESR1ESR2 | |
| SCHEMBL8157734 | 0.72 | MAOB (0.48) | ALDH1A1 | |
| SCHEMBL6561378 | 0.72 | — | — | |
| SCHEMBL7986098 | 0.69 | TSHR (0.33) | ALDH1A1TSHRESR1ESR2 | |
| SCHEMBL18579065 | 0.69 | — | — | |
| SCHEMBL5146811 | 0.69 | HCAR2 (0.46) | ALDH1A1 | |
| SCHEMBL18579012 | 0.67 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL7748544 | 0.67 | CA1 (0.44) | ALDH1A1 | |
| SCHEMBL7748547 | 0.67 | CA1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886638-A4 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2000-12-27 | — | — | EP | disclosed |
| EP-0886638-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997019092-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1997-05-29 | — | — | WO | disclosed |