Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989211 | 0.87 | ADRB2 (0.40) | ALDH1A1KMT2ALMNAADRB2ADRB1 | |
| SCHEMBL7992452 | 0.85 | LMNA (0.45) | ALDH1A1TDP1KMT2AMAPK1LMNA | |
| SCHEMBL7985722 | 0.84 | ALDH1A1 (0.38) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL7988294 | 0.83 | LMNA (0.37) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL7989368 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL7988757 | 0.82 | TDP1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL7988238 | 0.81 | TSHR (0.36) | ALDH1A1TDP1KMT2AMAPK1HIF1A | |
| SCHEMBL7986556 | 0.81 | LMNA (0.46) | ALDH1A1TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL7993433 | 0.81 | HTT (0.32) | ALDH1A1KMT2AHIF1ASMN1; SMN2HPGD | |
| SCHEMBL7992377 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |