Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989211 | 0.85 | ADRB2 (0.40) | LMNAKMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7986133 | 0.85 | ALDH1A1 (0.42) | LMNATDP1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7988757 | 0.76 | TDP1 (0.33) | TDP1ALDH1A1 | |
| SCHEMBL7985722 | 0.75 | ALDH1A1 (0.38) | LMNATDP1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7993433 | 0.75 | HTT (0.32) | KMT2AALDH1A1BLMCYP2C19CYP1A2 | |
| SCHEMBL7988704 | 0.73 | ALDH1A1 (0.32) | KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL7992377 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7989368 | 0.72 | ALDH1A1 (0.37) | LMNATDP1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7988689 | 0.71 | ALDH1A1 (0.39) | ALDH1A1KDM4ECYP2C9CYP2C19CYP1A2 | |
| SCHEMBL13577870 | 0.71 | LMNA (0.59) | LMNATDP1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |