Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985885 | 0.96 | SIGMAR1 (0.59) | SIGMAR1FAAHMEN1KMT2A | |
| SCHEMBL7983466 | 0.93 | MEN1 (0.56) | SIGMAR1MEN1KMT2AHTR2A | |
| SCHEMBL7971893 | 0.89 | MEN1 (0.52) | SIGMAR1MEN1KMT2A | |
| SCHEMBL7971782 | 0.84 | SIGMAR1 (0.69) | SIGMAR1FAAHADORA3HTR2AHTR7 | |
| SCHEMBL30671736 | 0.81 | SIGMAR1 (0.70) | SIGMAR1FAAHHTR7 | |
| SCHEMBL7989733 | 0.80 | SIGMAR1 (0.64) | SIGMAR1FAAHADORA3HTR2AHTR7 | |
| SCHEMBL7986224 | 0.77 | SIGMAR1 (1.00) | SIGMAR1FAAH | |
| SCHEMBL3712707 | 0.76 | MEN1 (0.59) | SIGMAR1MEN1KMT2A | |
| SCHEMBL8526553 | 0.76 | SIGMAR1 (0.59) | SIGMAR1KMT2AADORA3HTR2AHTR7 | |
| SCHEMBL27497536 | 0.76 | HTR2A (0.72) | HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |