Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983466 | 0.95 | MEN1 (0.56) | MEN1KMT2AKCNH2SIGMAR1POLB | |
| SCHEMBL7985885 | 0.94 | SIGMAR1 (0.59) | MEN1KMT2ASIGMAR1CHRM3 | |
| SCHEMBL7986228 | 0.89 | SIGMAR1 (0.63) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL7986044 | 0.85 | SIGMAR1 (0.55) | MEN1KMT2AKCNH2SIGMAR1ACHE | |
| SCHEMBL3712707 | 0.80 | MEN1 (0.59) | MEN1KMT2AKCNH2SIGMAR1POLB | |
| SCHEMBL7971891 | 0.78 | SIGMAR1 (0.80) | MEN1KMT2AKCNH2SIGMAR1ACHE | |
| SCHEMBL7989733 | 0.78 | SIGMAR1 (0.64) | SIGMAR1CHRM3 | |
| SCHEMBL25238918 | 0.76 | MEN1 (0.89) | MEN1KMT2AKCNH2SIGMAR1POLB | |
| SCHEMBL9054221 | 0.75 | L3MBTL1 (0.64) | MEN1KMT2AKCNH2SIGMAR1ACHE | |
| SCHEMBL8527247 | 0.74 | SIGMAR1 (0.75) | MEN1KMT2AKCNH2SIGMAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |