Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.45 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972882 | 0.89 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL7986415 | 0.87 | CA2 (0.50) | PTGS2CA2CA12CA9CHRNA7 | |
| SCHEMBL5311606 | 0.83 | CA2 (0.54) | PTGS2CA2CA12CA9CHRNA7 | |
| SCHEMBL6732794 | 0.80 | CA2 (0.54) | PTGS2CA2CA12CA9CA1 | |
| SCHEMBL7983203 | 0.80 | PTGS2 (0.63) | PTGS2CHRNA7PTGS1 | |
| Dimethylamine SCHEMBL7983206 | 0.80 | PTGS2 (0.54) | PTGS2CA2CA12CA9CHRNA7 | |
| SCHEMBL7989310 | 0.79 | PTGS2 (0.59) | PTGS2CA2CA12CA9CHRNA7 | |
| SCHEMBL6728392 | 0.77 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL7986480 | 0.76 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL7985400 | 0.74 | PTGS1 (0.55) | PTGS2CA2CA12CA9CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294568-B1 | ANTIINFLAMMATORY AGENTS AND ANTITUMOR AGENTS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENTS AND COX2 ENZYME INHIBITORS | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1048649-A1 | 5-ARYLPYRROLE DERIVATIVES | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |