Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311606 | 0.90 | CA2 (0.54) | PTGS2PTGS1CA2CA12CA9 | |
| SCHEMBL7989315 | 0.86 | PTGS2 (0.59) | PTGS2PTGS1GCGRMAPK14 | |
| SCHEMBL7986415 | 0.86 | CA2 (0.50) | PTGS2PTGS1CA2CA12CA9 | |
| SCHEMBL7985400 | 0.86 | PTGS1 (0.55) | PTGS2PTGS1CA2CA12CA9 | |
| SCHEMBL7986247 | 0.79 | PTGS2 (0.45) | PTGS2PTGS1CA2CA12CA9 | |
| Dimethylamine SCHEMBL7983206 | 0.78 | PTGS2 (0.54) | PTGS2PTGS1CA2CA12CA9 | |
| SCHEMBL7983203 | 0.78 | PTGS2 (0.63) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL7983135 | 0.78 | PTGS2 (0.57) | PTGS2GCGRMAPK14 | |
| SCHEMBL12692373 | 0.76 | CA12 (0.86) | PTGS2PTGS1CA2CA12CA9 | |
| SCHEMBL6725526 | 0.75 | CA12 (0.73) | PTGS2PTGS1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294568-B1 | ANTIINFLAMMATORY AGENTS AND ANTITUMOR AGENTS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENTS AND COX2 ENZYME INHIBITORS | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1048649-A1 | 5-ARYLPYRROLE DERIVATIVES | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |