Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7986172 | 0.89 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL7985927 | 0.85 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL5311606 | 0.82 | CA2 (0.54) | PTGS2CA2CA1CHRNA7CA12 | |
| SCHEMBL7986247 | 0.80 | PTGS2 (0.45) | PTGS2CA2CA1CHRNA7CA12 | |
| SCHEMBL7989310 | 0.78 | PTGS2 (0.59) | PTGS2CA2CA1CHRNA7CA12 | |
| Dimethylamine SCHEMBL7985933 | 0.77 | MAPK14 (0.51) | PTGS2PTGS1 | |
| SCHEMBL7983203 | 0.76 | PTGS2 (0.63) | PTGS2CHRNA7PTGS1 | |
| SCHEMBL6724544 | 0.75 | PTGS2 (0.73) | PTGS2CA2CA1CA12CA9 | |
| SCHEMBL28298612 | 0.74 | CA2 (0.75) | PTGS2CA2CA1CA12CA9 | |
| SCHEMBL7985400 | 0.74 | PTGS1 (0.55) | PTGS2CA2CA1CHRNA7CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294568-B1 | ANTIINFLAMMATORY AGENTS AND ANTITUMOR AGENTS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENTS AND COX2 ENZYME INHIBITORS | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1048649-A1 | 5-ARYLPYRROLE DERIVATIVES | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |